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Stem Cells

Working with Raw Materials

According to Mayo Clinic: “Stem cells are the body’s raw materials — cells from which all other cells with specialized functions are generated. Under the right conditions in the body or a laboratory, stem cells divide to form more cells called daughter cells. These daughter cells either become new stem cells (self-renewal) or become specialized cells (differentiation) with a more specific function, such as blood cells, brain cells, heart muscle cells or bone cells. No other cell in the body has the natural ability to generate new cell types.”

Stem cells produced inside the body are stimulated to grow in order to replace dead or dying tissues. Stem cells help keep the organs, bones, skin and other tissues healthy and helps slow the aging process. They also play a critical role in healing from injuries, infections and disease. Research has shown that stem cells continue to replicate and grow as the body ages but their functions may diminish in power. This may be why people lose muscle mass and skin vitality and experience slower recovery times as they age.

Hyperbaric oxygen therapy is playing a significant role in the study of increasing natural stem cell production and in boosting the effects of stem cell injection procedures for injuries and disease. Studies have shown after a series of hyperbaric treatments, stem cell counts increase much faster than without the treatments. Many physicians who utilize stem cell therapy for injuries and autoimmune disorders prescribe a series of hyperbaric treatments to help the stem cells stay in the system longer, encouraging more replication and tissue repair.
Stem Cell

To read more about stem cells from the Mayo Clinic, please click here.

Stem Cells: Studies, Articles and Videos

Stem Cell Mobilization by Hyperbaric Oxygen

Stephen R. Thom,Veena M. Bhopale, Omaida C. Velazquez, Lee J. Goldstein, Lynne H. Thom, and Donald B

Abstract

We hypothesized that exposure to hyperbaric oxygen (HBO2) would mobilize stem/progenitor cells from the bone marrow by a nitric oxide (·NO) -dependent mechanism. The population of CD34+ cells in the peripheral circulation of humans doubled in response to a single exposure to 2.0 atmospheres absolute (ATA) O2 for 2 h. Over a course of 20 treatments, circulating CD34+ cells increased eightfold, although the overall circulating white cell count was not significantly increased. The number of colony-forming cells (CFCs) increased from 16 ± 2 to 26 ± 3 CFCs/100,000 monocytes plated. Elevations in CFCs were entirely due to the CD34+ subpopulation, but increased cell growth only occurred in samples obtained immediately posttreatment. A high proportion of progeny cells express receptors for vascular endothelial growth factor-2 and for stromal-derived growth factor. In mice, HBO2 increased circulating stem cell factor by 50%, increased the number of circulating cells expressing stem cell antigen-1 and CD34 by 3.4-fold, and doubled the number of CFCs. Bone marrow ·NO concentration increased by 1,008 ± 255 nM in association with HBO2. Stem cell mobilization did not occur in knockout mice lacking genes for endothelial ·NO synthase. Moreover, pretreatment of wild-type mice with a ·NO synthase inhibitor prevented the HBO2-induced elevation in stem cell factor and circulating stem cells. We conclude that HBO2 mobilizes stem/progenitor cells by stimulating ·NO synthesis.

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Dr. Efrati enlightens us on stem cell therapy